What autoimmune diseases cause burning mouth
What autoimmune diseases cause burning mouth Autoimmune diseases are a group of complex conditions in which the body’s immune system mistakenly attacks its own tissues, leading to a wide array of symptoms and health issues. One particularly distressing symptom that some individuals experience is a burning sensation in the mouth, often described as a fiery or scalding feeling. This symptom can significantly impact quality of life, affecting eating, speaking, and overall comfort. Understanding which autoimmune diseases can cause burning mouth syndrome (BMS) is crucial for proper diagnosis and management.
Several autoimmune conditions are linked to burning mouth symptoms, with some being more common than others. One of the primary autoimmune diseases associated with burning mouth is Sjögren’s syndrome. This chronic disorder primarily targets moisture-producing glands, including those in the mouth and eyes. As salivary gland function diminishes, individuals often experience dry mouth—xerostomia—that can lead to a burning or sore sensation. The dryness reduces lubrication and natural protection of oral tissues, making them more susceptible to irritation, soreness, and burning sensations.
Lichen planus is another autoimmune condition that can cause burning mouth symptoms. It is a chronic inflammatory disease that affects mucous membranes inside the mouth. Patients with oral lichen planus often report burning or itching sensations, along with white, lacy patches or ulcers on the oral mucosa. The exact cause of lichen planus remains unknown, but immune system dysregulation plays a significant role. The persistent inflammation and immune attack on mucosal tissues contribute to the discomfort and burning sensation.
Another autoimmune disease that may cause burning mouth symptoms is systemic lupus erythematosus (SLE). SLE can affect multiple organs, including the skin and mucous membranes. Oral manifestations often include ulcers, dryness, and a burning sensation. The immune system’s attack on the mucosal tissues results in inflammation, which can cause discomfort and a burning feeling in the mouth.
Hashimoto’s thyroiditis, an autoimmune disorder affecting the thyroid gland, has also been associated with oral symptoms, including burning mouth. Although primarily known for causing hypothyroidism, which can lead to dry mouth and altered sensation, some patients report a

persistent burning feeling. The dryness and hormonal imbalances may contribute to mucosal irritation and discomfort.
In addition to these, other conditions such as autoimmune vasculitis and certain rare connective tissue diseases may also lead to oral burning sensations through inflammation and tissue damage. The common thread among these autoimmune diseases is immune dysregulation, which results in inflammation and tissue impairment within the oral cavity.
Diagnosing burning mouth syndrome related to autoimmune diseases involves a comprehensive medical history, clinical examination, and laboratory tests to identify underlying autoimmune activity. Treatment focuses on managing the autoimmune condition itself, alleviating dryness, reducing inflammation, and providing symptomatic relief. For example, patients may benefit from saliva substitutes, corticosteroids, or immune-modulating therapies, depending on the severity and specific diagnosis.
In conclusion, several autoimmune diseases such as Sjögren’s syndrome, lichen planus, systemic lupus erythematosus, and Hashimoto’s thyroiditis can cause burning mouth sensations. Recognizing the link between autoimmune disorders and oral symptoms is essential for timely diagnosis and effective treatment, ultimately improving patients’ quality of life.








