Palmoplantar Hyperkeratosis Causes

Palmoplantar Hyperkeratosis Causes Palmoplantar hyperkeratosis makes the skin on your hands and feet thick. It’s important to know why this happens for the right treatment. Many things can make the skin thicken, like genes, the environment, and other health issues.

Some people get it because of their genes. Being in the same place a lot can make it worse. Also, having skin problems like psoriasis or eczema can lead to it.

This starts our look into why palmoplantar hyperkeratosis happens. We’ll learn more about it to help manage it better.

Get Free Consultation

Please enable JavaScript in your browser to complete this form.
Step 1 of 4
Select Your Gender

ACIBADEM Health Point: The Future of Healthcare

We believe that everyone deserves access to quality healthcare, which is why we have established multiple branches in strategic locations. Whether you're in need of routine check-ups, specialized treatments, or emergency care, ACIBADEM Health Point is here for you.

Understanding Palmoplantar Hyperkeratosis

Palmoplantar hyperkeratosis is a skin condition that makes the palms and soles thick and hard. It’s part of a group called keratoderma. Knowing how it looks and the different types helps doctors diagnose and treat it.

Definition and Overview

This condition makes the outer skin layer too thick, especially on the palms and soles. It looks like hard, thick patches. These patches are uncomfortable and can be ugly.

They happen when the skin makes too much keratin, a protective protein. This leads to many skin problems.

ACIBADEM Health Point: Your Health is Our Priority!

ACIBADEM Health Point, we are dedicated to providing exceptional healthcare services to our patients. With a team of highly skilled medical professionals and state-of-the-art facilities, we strive to deliver the highest standard of care to improve the health and well-being of our patients. What sets ACIBADEM Health Point apart is our patient-centered approach. We prioritize your comfort, safety, and satisfaction throughout your healthcare journey. Our compassionate staff ensures that you receive personalized care tailored to your unique needs, making your experience with us as seamless and comfortable as possible.

Types of Hyperkeratosis

Knowing the types of hyperkeratosis helps doctors give the right treatment. The main types are:

  • Diffuse Palmoplantar Keratoderma: This makes the palms and soles very thick all over.
  • Focal Palmoplantar Keratoderma: This makes calluses in certain areas that get a lot of pressure.
  • Punctate Palmoplantar Keratoderma: This has many small, hard spots or thickened areas on the palms and soles.

Each type needs its own treatment. So, finding out the type early is very important.

Common Symptoms of Palmoplantar Hyperkeratosis

The symptoms of palmoplantar hyperkeratosis can really change your life. They make your skin thick and hard, causing pain and making things hard to do. Knowing about these symptoms helps manage them better.

Visible Signs

One big sign is thick skin on your palms and soles. You might see hyperkeratotic plaques, which are hard patches. These can be yellowish or brown and might cover a lot of skin or just a little bit.

Physical Discomfort

People with this condition often feel a lot of pain. The thick skin and hard patches can crack and bleed. This can hurt a lot and make you more likely to get infections. The pain can be mild or very bad, making it hard to move around.

Impact on Daily Activities

This condition makes everyday tasks hard. The pain and thick skin make it tough to walk or use your hands. It can stop you from working, playing, or even taking care of yourself. Plus, people might not want to be seen because of how it looks, which can make you feel bad about yourself.

Symptom Description Impact
Thickened Skin Noticeable thickening of skin on palms and soles Visible and palpable, affects aesthetics and movement
Hyperkeratotic Plaques Hardened patches of skin, often discolored Causes pain and discomfort, hinders daily activities
Cracking and Pain Fissures in the skin that can bleed Increases risk of infection, severe pain, limits mobility
See also  Annular Lichenoid Dermatitis Basics

Genetic Factors Contributing to Hyperkeratosis

Many cases of palmoplantar hyperkeratosis come from genes passed down in families. Knowing these factors helps in managing and spotting the condition early.

Inherited Conditions

Some inherited conditions lead to palmoplantar hyperkeratosis. These skin issues are linked to genes that help keep skin healthy.

  • Pachyonychia Congenita: A rare genetic disease causing thickened skin on the palms and soles, often with nail issues.
  • Vohwinkel Syndrome: A genetic issue that results in thickened skin in a honeycomb pattern.
  • Mal de Meleda: An autosomal recessive disorder with progressive thickening of skin on palms and soles.

Role of Family History

Family history is key in predicting hyperkeratosis. Families with a history of skin issues are more likely to see it in future generations. Knowing this can lead to early action and care.

Genetic counseling is great for families with skin disorder histories. It helps understand risks and what it means for inherited diseases. It also offers insights on treatments and ways to prevent it.

Acquired Keratoderma: Environmental Causes

Acquired keratoderma makes skin thick. It’s often caused by things around us. Knowing what causes it helps us prevent it.

Continuous Friction and Pressure

Palmoplantar Hyperkeratosis Causes  Friction and pressure make skin thicken. This happens when hands and feet get stressed. People with jobs or hobbies that put pressure on their hands and feet often get it.

  • Manual laborers who frequently handle tools
  • Athletes engaging in high-impact sports
  • Musicians, particularly guitarists and drummers

How long and what you do affects how bad it gets. Here’s how different jobs and activities change the skin:

Occupation/Activity Type of Pressure Associated Skin Thickening
Manual Labor (e.g., Construction) Continuous usage of tools Thickened skin areas on palms and fingers
Athletics (e.g., Running) Repeat impact on feet Calluses and hardened areas on soles
Musicians (e.g., Guitarists) Constant finger pressure on frets Thickened fingertips

We can fight skin thickening by changing how we act, using gear, and tools that help. By doing this, we can lessen the effects of acquired keratoderma.

Medical Conditions Linked to Palmoplantar Hyperkeratosis

Palmoplantar hyperkeratosis often goes with other skin issues, making it harder to handle. Knowing how these conditions work together helps patients and doctors. This way, they can manage symptoms better and improve life quality.


Psoriasis can make skin on palms and soles rough and scaly. This makes hyperkeratosis worse. It happens because psoriasis speeds up skin cell growth, causing thick skin.

Knowing about these links helps in finding better treatments.


Eczema makes skin itchy, red, and inflamed. It can make palmoplantar hyperkeratosis worse. Scratching can make skin thick and open to infections.

Understanding these links is key to helping patients feel better.

Managing these skin issues together is important. Patients and doctors can work together to lessen the effects of psoriasis, eczema, and other conditions. This helps reduce the severity of palmoplantar hyperkeratosis.

Role of Acibadem Healthcare Group in Treating Hyperkeratosis

The Acibadem Healthcare Group is a top place for dermatological care. They are experts in treating hyperkeratosis. They use the latest technology and a skilled team.

At Acibadem Healthcare Group, they make a special plan for each patient. First, they check deeply to find out why and how bad the palmoplantar hyperkeratosis is. Then, they pick the right treatments, like creams or procedures.

See also  Chickenpox Vs Smallpox: Key Differences Explained

The Acibadem Healthcare Group also teaches patients a lot. They give them the info they need to handle their condition well. This helps patients live better lives. The team makes sure patients know how to prevent and manage their dermatological care.

Service Details
Comprehensive Diagnosis Uses advanced tools for accurate diagnosis.
Topical Treatments Designed for the patient’s specific skin needs.
Patient Education Guidance on keeping skin healthy.
Supportive Care Long-term checks and support for the best results.

Effective Treatment Options for Palmoplantar Hyperkeratosis

Treating palmoplantar hyperkeratosis needs a full plan. This plan uses different methods to help manage and lessen symptoms. It includes topical therapiessystemic treatments, and procedures. Each method is chosen based on what the patient needs for the best results.

Topical Treatments

Topical therapies are often the first step against hyperkeratosis. They use things like salicylic acid, urea, and lactic acid to soften and remove thick skin. Moisturizers help keep the skin hydrated and work to keep its natural barrier strong.

Systemic Medications

For severe cases, doctors might use systemic treatments. Oral retinoids like acitretin and isotretinoin can help reduce skin thickness. Sometimes, drugs like methotrexate and cyclosporine are used for patients with inflammation that makes hyperkeratosis worse.

Procedural Interventions

Palmoplantar Hyperkeratosis Causes  For tough cases, doctors might use procedures. These include cryotherapy, chemical peels, and laser treatments. Cryotherapy uses cold to kill off bad skin cells. Chemical peels help remove old skin and make new skin grow. Laser therapy carefully removes thick skin to help skin grow back healthier.

By using these treatments together—like topical therapies, systemic medications, and procedures—doctors can help manage this condition. This helps improve the quality of life for patients with hyperkeratosis.

Importance of Foot Care Management

For people with palmoplantar hyperkeratosis, taking good care of your feet is key. It helps prevent problems. Make sure to follow a daily routine and wear shoes that protect your feet.

Daily Hygiene Practices

Keeping your feet clean every day is important. Start by washing them with mild soap and warm water. Dry them well, paying extra attention between the toes.

Exfoliating helps get rid of dead skin. Then, use a special moisturizer to keep your feet soft and moist.

Protective Footwear

Wearing shoes that protect your feet is crucial. Pick ones with good cushioning and support. This helps reduce pressure and friction.

Avoid shoes that are too tight, as they can make things worse. Choose shoes made of breathable materials. If needed, use orthotic inserts to help prevent problems.

Aspect Recommended Practices
Daily Skin Care Clean with mild soap, exfoliate regularly, use therapeutic moisturizers
Footwear Selection Cushioned, supportive, breathable, orthotic inserts if needed
Monitoring Regularly inspect feet for signs of complication, seek medical advice if needed

How to Prevent Thickened Skin and Hyperkeratotic Plaques

Palmoplantar Hyperkeratosis Causes  Some things that cause thickened skin can’t be changed. But, there are steps you can take to lower the risk. These steps include changing your habits and avoiding things that can make the skin thick.

Lifestyle Changes

Changing your lifestyle is key to preventing thickened skin. Drinking lots of water helps keep your skin healthy. Putting moisturizer on your skin keeps it elastic and stops it from getting dry.

Eating the right foods is also important. Eating foods high in vitamins A and E, like carrots and spinach, is good for your skin. Omega-3 fatty acids in fish and flaxseeds can also help keep your skin healthy.

See also  Best Dermatitis Creams: Nombres de Cremas Para la Dermatitis

Avoiding Environmental Triggers

It’s important to avoid things that can make your skin thick. Wearing shoes that fit well and doing activities gently can help. This reduces pressure on your feet and hands.

Also, keep your skin away from harsh chemicals and irritants. Wearing gloves when you’re using cleaners or other things that could irritate your skin helps. Keeping your skin clean and dry is also good for it.

By making these changes and avoiding things that can harm your skin, you can help prevent thickened skin and hyperkeratotic plaques. Here’s a table with more details on how to prevent these issues:

Preventive Measure Action Expected Benefit
Hydration Drink sufficient water daily Maintains skin elasticity and moisture
Moisturizing Apply moisturizer regularly Prevents dryness and cracking
Dietary Adjustments Consume foods rich in vitamins A, E, and Omega-3 Supports overall skin health
Comfortable Footwear Wear well-cushioned shoes Reduces friction and pressure on feet
Protective Gear Use gloves when handling irritants Avoids skin irritation and thickening
Proper Hygiene Keep skin clean and dry Prevents infections and maintains skin health

When to Seek Medical Advice for Skin Conditions

Knowing when to get help for skin problems is key. Getting help early can stop long-term pain and serious issues. It’s important to know your skin’s signs to know when to see a doctor.

Signs you need a doctor include constant itching, big changes in skin look or color, and strange growths. If home treatments don’t work or if things get worse, see a dermatologist.

At the doctor’s office, they will check your skin closely. They’ll want to know about your health, daily life, and past treatments. This helps them find the right treatment for you. Getting advice early can make a big difference in how well you do.

For skin issues like palmoplantar hyperkeratosis, seeing a doctor quickly is crucial. Following the treatment plan closely can really help. Don’t wait to get medical help if you have ongoing or bad symptoms. Early action often means better results.

Empowering Patients with Knowledge

Palmoplantar Hyperkeratosis Causes  Learning about palmoplantar hyperkeratosis helps patients make smart health choices. It lowers worry and leads to better health care. By teaching patients, they can talk better with doctors about treatments.

Knowing about hyperkeratosis helps patients speak up in the doctor’s office. They can explain their symptoms well. This helps doctors make a plan just for them.

Patients get to look at the good and bad of different treatments. This helps them make choices that fit what they need and like. Education is key to making smart health choices.

Teaching about palmoplantar hyperkeratosis is more than just facts. It includes tips on how to live with it, how to cope, and how to prevent it. This helps patients handle their condition every day. By focusing on education, we show its importance in making patients aware and in charge of their health.


What causes palmoplantar hyperkeratosis?

This condition makes the skin on palms and soles thick. It can come from genes, the environment, or other health issues like psoriasis or eczema.

What are the types of hyperkeratosis?

There are different kinds of hyperkeratosis. These include palmoplantar hyperkeratosis and other types. They make the skin thick and hard, usually on palms and soles.

Are there genetic conditions that contribute to palmoplantar hyperkeratosis?

Yes, many cases are linked to genes. Family history and inherited conditions increase the chance of getting it.

ACIBADEM Healthcare Group Hospitals and Clinics

With a network of hospitals and clinics across 5 countries, including 40 hospitalsACIBADEM Healthcare Group has a global presence that allows us to provide comprehensive healthcare services to patients from around the world. With over 25,000 dedicated employees, we have the expertise and resources to deliver unparalleled healthcare experiences. Our mission is to ensure that each patient receives the best possible care, supported by our commitment to healthcare excellence and international healthcare standards. Ready to take the first step towards a healthier future? Contact us now to schedule your Free Consultation Health session. Our friendly team is eager to assist you and provide the guidance you need to make informed decisions about your well-being. Click To Call Now !

*The information on our website is not intended to direct people to diagnosis and treatment. Do not carry out all your diagnosis and treatment procedures without consulting your doctor. The contents do not contain information about the therapeutic health services of ACIBADEM Health Group.