What autoimmune diseases cause cherry angiomas
What autoimmune diseases cause cherry angiomas Autoimmune diseases are conditions in which the immune system mistakenly attacks the body’s own tissues, leading to a wide range of symptoms and complications. Among the many dermatological manifestations associated with autoimmune disorders, cherry angiomas—small, bright red or purple benign skin growths—are of particular interest. While generally common and harmless, understanding the potential link between autoimmune diseases and cherry angiomas can aid in early diagnosis and comprehensive patient care.
Cherry angiomas are clusters of tiny blood vessels that form benign tumors on the skin. They usually appear as small, rounded, and smooth-red or purple bumps, typically on the trunk or extremities. These vascular lesions are common in adults, especially with advancing age, and are often considered a cosmetic concern rather than a medical one. However, in some cases, their sudden appearance or increase in number might signal underlying systemic issues, including autoimmune diseases.
Certain autoimmune conditions have been observed to have an association with vascular abnormalities, which may include the development of cherry angiomas. For instance, autoimmune connective tissue diseases such as systemic sclerosis (scleroderma) can involve vascular changes in the skin and internal organs. The pathology of systemic sclerosis includes abnormal collagen deposition and vascular damage, which can contribute to the formation of vascular proliferations, including cherry angiomas. Patients with systemic sclerosis often exhibit Raynaud’s phenomenon and digital ulcers, but some may also develop skin vascular lesions resembling cherry angiomas.
Lupus erythematosus, another autoimmune disorder, can cause various skin lesions, including vascular abnormalities. While lupus mainly manifests with butterfly rashes and photosensitivity, vasculitis—an inflammation of blood vessels—is also a common feature. Chronic vasculitis can lead to proliferation of blood vessels and may sometimes present with cherry angioma-like lesions, although these are less typical than in other vascular conditions.
Another autoimmune disease associated with vascular involvement is dermatomyositis. This condition causes inflammation of the skin and muscles, often with characteristic skin rashes. Vascular damage and proliferation are part of its pathology, and while cherry angiomas are not a diagnostic hallmark, vascular skin lesions can sometimes be present.

It’s important to note that cherry angiomas are primarily benign and common in the general population, especially with aging. The presence of these lesions alone is rarely diagnostic of an underlying autoimmune disease. However, if they appear suddenly, increase rapidly, or are accompanied by other systemic symptoms such as skin rashes, joint pain, or organ involvement, medical evaluation is warranted. Dermatologists and rheumatologists can perform thorough assessments, including skin biopsies and blood tests, to determine if an autoimmune process is contributing.
In summary, while cherry angiomas are generally benign and age-related, certain autoimmune diseases—particularly systemic sclerosis, lupus erythematosus, and dermatomyositis—may be associated with vascular changes that could manifest as or be linked to cherry angiomas. Recognizing these associations can aid clinicians in diagnosing underlying autoimmune conditions and providing appropriate management.
Understanding the relationship between autoimmune diseases and skin lesions like cherry angiomas underscores the importance of comprehensive health evaluation. Patients noticing new or changing skin lesions should seek medical advice, especially if accompanied by other systemic symptoms, to ensure timely diagnosis and treatment.








