What autoimmune diseases can cause hair loss
What autoimmune diseases can cause hair loss Autoimmune diseases are conditions in which the immune system mistakenly attacks the body’s own tissues, leading to a wide range of health issues. Among these, hair loss is a common yet often distressing symptom that can significantly impact a person’s self-esteem and quality of life. Several autoimmune diseases are known to cause hair loss, either directly through immune-mediated destruction of hair follicles or indirectly through inflammation and systemic effects.
One of the most well-known autoimmune diseases associated with hair loss is alopecia areata. This condition occurs when the immune system targets hair follicles, leading to patchy hair loss that can affect the scalp and other areas of the body. Alopecia areata can develop suddenly and may progress to complete scalp hair loss (alopecia totalis) or total body hair loss (alopecia universalis). The exact cause is unknown, but genetic predisposition and environmental triggers are believed to play roles.
Another autoimmune disorder linked to hair loss is systemic lupus erythematosus (SLE), often simply called lupus. Lupus is a chronic inflammatory disease that can affect the skin, joints, kidneys, and other organs. When the skin is involved, it can lead to a characteristic “butterfly” rash across the cheeks and nose. Hair loss in lupus tends to be diffuse and can occur due to inflammation of the scalp’s blood vessels, scarring, or as a side effect of medications used to treat the disease. The hair often regrows once the disease is controlled, but scarring can cause permanent hair loss if severe.

Thyroid autoimmune diseases, such as Hashimoto’s thyroiditis and Graves’ disease, are also associated with hair loss. Hashimoto’s disease, which causes hypothyroidism, can lead to thinning hair and hair fragility, especially around the scalp and eyebrows. Conversely, hyperthyroidism from Graves’ disease can cause hair thinning and scalp discomfort. The hair loss in these conditions is generally reversible with proper management of thyroid hormone levels, but ongoing imbalance can sustain hair thinning over time.
Other autoimmune conditions like scleroderma and dermatomyositis can also affect hair growth, primarily through skin changes and inflammation. Scleroderma causes hardening and tightening of the skin, which can lead to hair loss if it affects the scalp. Dermatomyositis, characterized by muscle weakness and skin rashes, may also involve scalp inflammation resulting in hair thinning.
In addition to these specific diseases, autoimmune-related inflammation and immune dysregulation can sometimes exacerbate existing hair loss conditions or complicate other causes of alopecia. Treatment typically involves managing the underlying autoimmune disease with immunosuppressants, corticosteroids, or other targeted therapies. Addressing the autoimmune component often results in hair regrowth or stabilization of hair loss.
Understanding the link between autoimmune diseases and hair loss is essential for early diagnosis and effective management. If hair loss occurs alongside other symptoms like fatigue, joint pain, skin rashes, or systemic changes, consulting a healthcare professional is crucial. Proper diagnosis and treatment can significantly improve outcomes, restoring both health and confidence.









