What autoimmune disease causes sternum pain
What autoimmune disease causes sternum pain Autoimmune diseases are conditions in which the body’s immune system mistakenly attacks its own tissues, leading to inflammation, pain, and tissue damage. Among the various symptoms these diseases can cause, chest pain, particularly around the sternum (breastbone), is a common but often misunderstood manifestation. Understanding which autoimmune diseases can cause sternum pain is essential for prompt diagnosis and effective management.
One of the primary autoimmune diseases associated with sternum pain is rheumatoid arthritis (RA). While RA predominantly affects the small joints in the hands and feet, it can also involve the ribs and sternum, leading to a condition called costochondritis. Costochondritis is characterized by inflammation of the cartilage that connects the ribs to the sternum, resulting in localized chest pain that can mimic heart-related issues. Patients typically report tenderness over the costosternal joints, and the pain may worsen with movement or deep breathing.
Another autoimmune condition that can cause sternum pain is systemic lupus erythematosus (SLE). Lupus is a multisystem disease that can involve the lungs, heart, skin, joints, and blood vessels. When the pleura (the lining surrounding the lungs) or the pericardium (the sac around the heart) become inflamed—a condition known as pleuritis or pericarditis—patients may experience sharp chest pains that can radiate to the sternum or mimic cardiac problems. Pericarditis, in particular, is a notable cause of chest pain in lupus, often described as a stabbing or burning sensation that worsens when lying down or taking deep breaths.
Another autoimmune disease that can cause sternum pain is ankylosing spondylitis, a form of inflammatory arthritis primarily affecting the spine and sacroiliac joints. As the disease progresses, inflammation can extend to the costosternal joints, causing pain and stiffness in the chest area. Patients may notice a deep, persistent ache in the sternum, often worsening with activity or during flare-ups.

Sarcoidosis, an inflammatory disease characterized by the formation of granulomas in various organs, can also involve the lungs and lymph nodes near the chest. When the lungs or pleura are affected, patients may experience chest discomfort or pain, sometimes perceived as sternum pain. Although less common, sarcoidosis-related chest pain can be part of systemic involvement leading to respiratory symptoms.
Diagnosing autoimmune-related sternum pain involves a comprehensive approach, including clinical evaluation, laboratory tests for autoimmune markers, imaging studies like X-rays, MRI, or ultrasound, and sometimes biopsy. Since chest pain can also be caused by cardiac or pulmonary conditions, ruling out life-threatening issues is crucial. Treatment typically focuses on controlling the underlying autoimmune process with medications such as corticosteroids, immunosuppressants, or disease-modifying antirheumatic drugs (DMARDs).
In summary, several autoimmune diseases can lead to sternum or chest wall pain, primarily through inflammation of the cartilage, joints, or lining of the lungs and heart. Recognizing the symptoms and understanding their autoimmune origins are vital steps toward effective treatment and relief from discomfort.









