What autoimmune disease causes night sweats
What autoimmune disease causes night sweats Autoimmune diseases are conditions where the body’s immune system mistakenly attacks its own tissues, leading to a wide array of symptoms and complications. Among these symptoms, night sweats can be particularly distressing and disruptive, often prompting individuals to seek medical attention. While night sweats are commonly associated with infections or hormonal changes, certain autoimmune diseases are known to cause this symptom.
One of the autoimmune diseases most frequently linked with night sweats is systemic lupus erythematosus (SLE). Lupus is a chronic condition characterized by widespread inflammation affecting multiple organs, including the skin, joints, kidneys, and nervous system. The immune system’s abnormal activity in lupus can lead to fever, fatigue, joint pain, and, notably, night sweats. These sweats often occur due to the body’s ongoing inflammatory response and the systemic nature of the disease, which can cause fluctuations in body temperature and overall metabolic activity.
Another autoimmune disorder associated with night sweats is rheumatoid arthritis (RA). While primarily known for joint inflammation and deformity, RA can also cause systemic symptoms such as fever and night sweats, especially during disease flare-ups. The chronic inflammation inherent in RA can influence the body’s temperature regulation, leading to episodes of excessive sweating during the night. Additionally, some medications used to treat RA, such as biologic agents and immunosuppressants, can contribute to night sweats as side effects.
Hashimoto’s thyroiditis, an autoimmune condition where the immune system attacks the thyroid gland, can also be linked with night sweats. Although it more commonly causes hypothyroidism, some individuals may experience fluctuating thyroid hormone levels, leading to symptoms like hot flashes and night sweats. These hormonal shifts interfere with normal temperature regulation, manifesting as excessive sweating during sleep.
Multiple sclerosis (MS), another autoimmune disorder affecting the central nervous system, can sometimes be associated with night sweats. While MS primarily causes neurological symptoms such as muscle weakness and coordination issues, it can also lead to autonomic dysfunction—the impairment of the body’s automatic processes, including temperature regulation. Autonomic nervous system involvement may result in abnormal sweating patterns, including night sweats.

In addition to these specific autoimmune diseases, systemic autoimmune conditions like vasculitis—an inflammation of blood vessels—can also cause night sweats. The ongoing inflammation and immune activation in vasculitis can impact the body’s temperature regulation mechanisms, leading to episodes of excessive sweating, often accompanied by fever and other systemic symptoms.
It’s important to recognize that night sweats can be caused by various factors, including infections, hormonal changes, medications, and cancer. Therefore, when night sweats are persistent or severe, consulting a healthcare professional is crucial for proper diagnosis and management. Blood tests, imaging, and a thorough clinical evaluation can help identify underlying autoimmune conditions and guide appropriate treatment strategies.
Understanding the connection between autoimmune diseases and night sweats highlights the importance of comprehensive medical assessment for symptoms that disrupt daily life. Managing the underlying autoimmune disorder often alleviates symptoms like night sweats, improving overall quality of life and well-being.









