The Total Anterior Circulation Stroke Radiology Insights
The Total Anterior Circulation Stroke Radiology Insights A total anterior circulation stroke (TACS), also known as a “complete” or “large vessel” stroke, involves widespread ischemia affecting multiple territories supplied by the anterior circulation of the brain. These territories include the regions supplied by the internal carotid artery, such as the middle cerebral artery (MCA), anterior cerebral artery (ACA), and their branches. Recognizing the radiologic features of TACS is essential for prompt diagnosis, treatment planning, and prognosis assessment.
On neuroimaging, computed tomography (CT) remains the first-line modality in the acute setting. Typically, a non-contrast CT scan may initially appear normal, especially within the first few hours post-onset. However, subtle signs such as loss of gray-white matter differentiation, sulcal effacement, and hypodensity in the MCA territory can suggest early ischemia. As the stroke evolves, these changes become more pronounced, revealing extensive hypoattenuation across the affected regions. The early detection of hyperdense artery signs, particularly in the internal carotid or the proximal segments of the MCA, indicates a clot presence and can guide interventions like thrombolysis or thrombectomy. The Total Anterior Circulation Stroke Radiology Insights
Magnetic resonance imaging (MRI), especially diffusion-weighted imaging (DWI), provides more sensitive detection of acute ischemia. In TACS, DWI typically shows extensive hyperintense areas corresponding to infarction across the MCA and ACA territories, often involving the frontal, parietal, and temporal lobes. The involvement of both superficial and deep structures, such as the basal ganglia and internal capsule, underscores the severity of the infarct. Fluid-attenuated inversion recovery (FLAIR) images assist in estimating the age of the infarct, with hyperintensity appearing as the ischemia matures.
The Total Anterior Circulation Stroke Radiology Insights Vessel imaging, including CT angiography (CTA) or MR angiography (MRA), plays a critical role in visualizing large vessel occlusions. In TACS, angiography often reveals occlusion or significant stenosis of the cervical internal ca

rotid artery and embolic or thrombotic occlusion of the MCA main stem. These findings are crucial for determining eligibility for endovascular therapy and predicting outcomes.
Beyond the primary infarct, secondary radiologic features such as cerebral edema, mass effect, and early signs of hemorrhagic transformation are important considerations. Massive infarcts can lead to midline shift and increased intracranial pressure, which are documented through serial imaging. Recognizing these complications promptly can influence management strategies, including surgical decompression. The Total Anterior Circulation Stroke Radiology Insights
The Total Anterior Circulation Stroke Radiology Insights Understanding the radiology of TACS is fundamental for clinicians and radiologists alike. The extensive involvement seen on imaging correlates with the profound neurological deficits observed clinically, including hemiplegia, aphasia, and hemianopia. Early detection and accurate characterization of the infarct extent facilitate timely interventions, potentially reducing morbidity and mortality associated with this devastating stroke subtype.
The Total Anterior Circulation Stroke Radiology Insights In conclusion, radiologic insights into total anterior circulation stroke emphasize the importance of a multimodal imaging approach—combining CT, MRI, and vascular imaging—to comprehensively assess the extent, location, and vascular etiology of the infarct. This integrated perspective enhances treatment decision-making and improves patient outcomes.









