The Cor Pulmonale ECG Findings
The Cor Pulmonale ECG Findings Cor pulmonale refers to the alteration and failure of the right ventricle of the heart caused by pulmonary hypertension secondary to chronic lung diseases or pulmonary vascular disorders. One of the key diagnostic tools for identifying and assessing cor pulmonale is the electrocardiogram (ECG). Recognizing specific ECG findings associated with cor pulmonale is crucial for timely diagnosis, management, and prognosis.
In patients with cor pulmonale, the ECG typically exhibits signs of right ventricular hypertrophy (RVH), which results from the increased workload on the right ventricle due to elevated pulmonary arterial pressures. These electrical changes are often evident in the limb leads, especially lead V1, V2, V5, and V6. The classic ECG findings include right axis deviation, which reflects the increased dominance of right-sided electrical activity. The QRS axis in cor pulmonale usually shifts to the right, often beyond +90 degrees.
Right ventricular hypertrophy manifests on the ECG as a tall R wave in V1, often exceeding 7 mm in amplitude, paired with a deep S wave in V6. The R/S ratio in V1 becomes greater than 1, indicating hypertrophy of the right ventricle. Additionally, right atrial enlargement, which may coexist with RVH, can produce peaked P waves in leads II, III, and aVF, known as P pulmonale. These peaked P waves are typically greater than 2.5 mm in height, reflecting right atrial dilation.
Another hallmark finding is the presence of right bundle branch block (RBBB) pattern, which appears as an rsR’ pattern in V1 and V2, with wide QRS complexes exceeding 120 milliseconds. The RBBB pattern signifies delayed conduction through the right bundle branch, often due to right ventricular dilation and strain. The T wave

changes are also noteworthy; inverted T waves in V1-V3 suggest right ventricular strain and repolarization abnormalities.
The ECG may also reveal signs of right atrial and ventricular overload, such as increased P wave amplitude and right axis deviation. The combination of these features underscores the presence of right-sided cardiac involvement secondary to pulmonary pathology. However, it is important to note that ECG findings are not always specific or sensitive; some patients with cor pulmonale may have subtle or even normal ECGs, necessitating correlation with clinical and echocardiographic findings.
In summary, the ECG provides valuable clues in diagnosing cor pulmonale. Key findings include right axis deviation, right ventricular hypertrophy, RBBB pattern, P pulmonale, and right ventricular strain patterns. Recognizing these signs helps clinicians identify right heart strain early, guiding further investigations and management strategies to improve patient outcomes.
Understanding the ECG features of cor pulmonale enhances clinical assessment, especially in patients with known pulmonary disease or unexplained right heart failure symptoms. While ECG is a useful screening tool, it should always be complemented by echocardiography and other imaging modalities for comprehensive evaluation.









