The Cervical Chordoma Radiology Features
The Cervical Chordoma Radiology Features The cervical chordoma is a rare malignant tumor arising from remnants of the notochord within the cervical spine. Its diagnosis and management heavily rely on radiological imaging, which provides critical insights into its characteristic features, extent, and relationship with surrounding structures. Radiologically, cervical chordomas typically present as midline, destructive lesions involving the vertebral bodies. On plain radiographs, they may appear as lytic, expansile masses with irregular borders, often causing vertebral body destruction and soft tissue swelling. However, due to limited soft tissue detail, advanced imaging modalities like computed tomography (CT) and magnetic resonance imaging (MRI) are essential for comprehensive assessment.
CT scans are particularly valuable in evaluating the bony component of the tumor. They reveal a destructive, osteolytic lesion with poorly defined margins, often accompanied by areas of calcification or ossification within the mass. The presence of calcifications is a characteristic feature of chordomas and can help differentiate them from other neoplasms. Additionally, CT provides detailed information about the extent of bony destruction, involvement of the vertebral bodies, and any potential epidural extension or foraminal encroachment, which are critical for surgical planning.
MRI remains the gold standard for soft tissue characterization and delineation of tumor extent. On MRI, cervical chordomas typically appear as lobulated, midline masses with heterogeneous signal intensity. They generally exhibit low to intermediate signal on T1-weighted images and high signal on T2-weighted images, reflecting their high water content and myxoid matrix. The heterogeneity may be due to necrosis, hemorrhage, or calcifications within the tumor. Post-contrast imaging often shows heterogeneous enhancement, highlighting viable tumor tissue and aiding in assessing infiltration into adjacent structures such as the spinal cord, nerve roots, prevertebral, and paravertebral tissues.
A hallmark radiologic feature of cervical chordomas is their tendency to invade surrounding bones and soft tissues, often crossing the midline and extending into the prevertebral space. They may cause compression or displacement of the spinal cord, leading to neurological symptoms. The tumor’s lobulated nature and its destructive pattern help distinguish it from other spinal neoplasms, such as chondrosarcomas or metastases. Additionally, the absence of significant periosteal reaction, common in benign lesions, supports the diagnosis of a malignant process.
The radiological evaluation also plays a pivotal role in distinguishing chordomas from other entities like ecchordosis physaliphora, which are benign notochordal remnants, and other malignancies such as metastatic carcinomas or primary neurogenic tumors. The combination of imaging features—midline location, destructive vertebral involvement, characteristic calcifications, and high T2 signal intensity—are key clues for diagnosis.
In conclusion, radiology provides a comprehensive window into the complex nature of cervical chordomas. The integration of CT and MRI findings enables accurate delineation of the tumor, assessment of local invasion, and surgical planning, ultimately improving prognosis and guiding appropriate treatment strategies.
